Lipid measures are associated with cognitive functioning in multiple sclerosis

[Prot]

Highlights


•
Growing evidence links dyslipidemia to cognitive outcomes in MS patients.


•
Study analyzed 211 MS patients with 361 timepoints over 15 years.


•
Elevated LDL-C correlates with lower cognitive performance in MS.


•
Higher HDL-C is associated with lower PASAT-3 scores in MS patients.


•
Adverse lipid profiles impact cognitive function in MS, independent of brain atrophy.



Only registered and activated users can see links., Click Here To Register...

[agate]

Interesting. Some years ago there was some excitement about a possible improvement in MS if one of the cholesterol-lowering drugs was prescribed--simvastatin. I'm not sure why that statin drug was chosen because there are several other statins (I take atorvastatin, for instance) but maybe there was something about simvastatin in particular.

For instance, there was this:

Only registered and activated users can see links., Click Here To Register...

Looks as if the experts are still exploring a connection between MS and cholesterol.

[Virginia]

There was, at one time, something about Zocor being helpful. There was also a third one that XoXo took.

[agate]

I recall that xoxo (Mark) took CoQ 10 but can't recall other drugs or supplements he might have been taking.

[Virginia]

He also took a statin. He said it was a high dose.

[agate]

I'd forgotten that. He was on Copaxone, at least for a while. He was woodrow here before he was xoxo or was it xoxo++?

[Virginia]

His name was Mark and he changed it when the board went down one time. I wasn't aware that he went by Woodrow.

[agate]

Do you recall that he returned a few years ago just to say Hi, and it turned out that he had married a neurologist? I seem to recall that the neurologist was Russian.

[Virginia]

Yes, I do remember him stopping by. I wish he would stop in again.