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From adaptive to maladaptive hippocampal resting-state functional connectivity

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    From adaptive to maladaptive hippocampal resting-state functional connectivity

    Abstract


    Background

    It remains unclear how resting-state functional connectivity (rsFC) changes in the hippocampus modulate the negative impact of white matter (WM) lesions on memory performance over the course of multiple sclerosis (MS). This study investigates whether hippocampal rsFC alterations at each MS clinical stage affect memory performance.
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    Yet inside there is this perpetual nagging doubt;
    the feeling we are possessed by a 'subtle lack of togetherness''.

    #2
    Thank you for finding and posting this.

    They keep trying to match up MS symptoms with a specific location in the brain where there might be a lesion that is causing those symptoms. I'm not sure how much they actually know about locating the source of specific symptoms but at least they do keep trying.
    SPMS diagnosed 1980. Avonex 2001-2004. Copaxone 2006-2009. Glatopa (glatiramer acetate = Copaxone) 12/20 - 3/19/24.

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