These fat-filled brain cells may be making multiple sclerosis worse

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Date:June 29, 2026Source:Netherlands Institute for Neuroscience -

KNAWSummary:Scientists have uncovered a surprising clue that may help explain why multiple sclerosis (MS) progresses rapidly in some people but not others. In brain tissue from patients with severe MS, researchers found large numbers of “foamy” immune cells packed with fat droplets after absorbing damaged myelin. These overloaded cells appear to switch from helping repair the brain to fueling ongoing damage and inflammation.

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This looks important even if it was a small study. Or maybe it's just that the phrase "foamy microglia" is so unappealing that a person is inclined to feel they have to be important. I'm sure nobody wants to hear that their brain is filled with foamy microglia.

It just doesn't sound healthy. I have the same problem with "neurofibrillary tangles"--I believe they crop up in Alzheimer's disease.

Thank you for posting this, Tim.