Patients sue Biogen over PML from Tysabri

[stillstANNding]

Today's Boston Globe:

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ANN

[Frog42]

It's like Russian Roulette all right. Glad I never tried it.

[stillstANNding]

Sorry, wrong thread.

ANN

[agate]

ANN, thanks so much for calling attention to this.

For those who've been wondering how the patients on Tysabri who got PML are doing, the story tells about two of them.

Are they supposed to be glad they didn't die of PML, or what? Surely the quality of their lives has deteriorated, and yet we've had upbeat reports about how PML hasn't affected MS patients on Tysabri nearly as badly as it typically affects some other people--such as those with AIDS.

Looks as if Big Pharma people has been a bit too eager to jump on the very profitable MS drug bandwagon.

[SalpalSally]

About time...GRRRR!!!

[Cherie]

Biogen sponsored a 4 year clinical trial to test the effectiveness of their blood test for JC Virus. I enrolled. The first 2 years, I tested JCV negative and last year, I tested positive. No illnesses or infections in the meantime. I was also on Cytoxan during the first two testing periods and not during the third. There is no way, testing positive, and having been on immunosuppressive therapy for a lengthy period, that I would ever consider going on the drug, no matter how effective it is.

[renee]

I had no idea that there was possible permanent damage after successful treatment of PML.
Thank you for the enlightenment.

Rug burns associated with reactions to Tecfidera go away, right?

[agate]

renee, this is from the Tecfidera Website:

 flushing, redness, itching, or rash  nausea, vomiting, diarrhea, stomach pain, or indigestion
Flushing and stomach problems are the most common reactions, especially at the start of therapy, and may decrease over time. Call your doctor if you have any of these symptoms and they bother you or do not go away.
These are not all the possible side effects of TECFIDERA. Call your doctor for medical advice about side
effects. You may report side effects to FDA at 1-800-FDA-1088. For more information go to
dailymed.nlm.nih.gov.

I'm not sure if that's what you meant by rug burns but apparently any side effects might go away, and then again they might not, and if they don't, you're asked to report them.

As for the PML patients who'd been on Tysabri, this article is a couple of years old but has some information:

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