Ocrelizumab (Ocrevus) dosing--this is from a .pdf file from the Ocrevus Website.
Recommended dose and dose administration
• The initial 600 mg dose is administered as 2 separate intravenous infusions given over approximately 2.5 hours:first as a 300 mg intravenous infusion followed 2 weeks later by a second 300 mg intravenous infusion*
• Subsequent doses are administered over approximately 3.5 hours as a single 600 mg intravenous infusionevery 6 months*
• Observe the patient for at least 1 hour after the completion of the infusion
Single infusionDoses of OCREVUSmust be separated by atleast 5 months.
Delayed or missed doses
• If a planned infusion of OCREVUS is missed, administer OCREVUS as soon as possible; do not waituntil the next scheduled dose• Reset the dose schedule to administer the next sequential dose 6 months after the missed doseis administered
*Infusion time may take longer if the infusion is interrupted or slowed
• The initial 600 mg dose is administered as 2 separate intravenous infusions given over approximately 2.5 hours:first as a 300 mg intravenous infusion followed 2 weeks later by a second 300 mg intravenous infusion*
• Subsequent doses are administered over approximately 3.5 hours as a single 600 mg intravenous infusionevery 6 months*
• Observe the patient for at least 1 hour after the completion of the infusion
Single infusionDoses of OCREVUSmust be separated by atleast 5 months.
Delayed or missed doses
• If a planned infusion of OCREVUS is missed, administer OCREVUS as soon as possible; do not waituntil the next scheduled dose• Reset the dose schedule to administer the next sequential dose 6 months after the missed doseis administered
*Infusion time may take longer if the infusion is interrupted or slowed
Comment