Neck pain induced by the biological clock

[clouds z]

TURN OFF WIFI
USE THE CORD TO COMPUTER
CALL ISP TO LEARN HOW

[clouds z]

i had neck pain at age 12 - i blame overheard power wires etc

[Piergino Pedrocco]

I apologize to clouds z for my late reply.
My problem started before WiFi. So, it can't be that. Anyway, thank you for your interest.

Asking again Gemini, I had a second hypothesis, maybe closer to reality.

After a generic question, I had a generic answer (not a neurological, but a muscular problem).

I quote an excerpt, which I translated online,

Postural Dysfunction or Fatigue: If the person maintains suboptimal posture during the hours they stand (perhaps with their head forward or shoulders hunched), the neck muscles (especially the trapezius and levator scapulae muscles) are forced to work much harder to stabilize the head. This prolonged exertion, especially when exceeding the "time limit" of muscular endurance, leads to a painful contracture that manifests itself the following morning as discomfort or stiffness.

Cumulative Muscular Fatigue: The discomfort arises after the muscles have been subjected to the load for the entire day. The evening moment, when the muscles are most tired and the compensation mechanisms give way, is the point at which the effort to maintain orthostatism (standing) becomes unsustainable, triggering the painful reaction at night and in the morning.

Stress and Tension: Emotional stress or nervous tension are known factors that lead to involuntary and chronic contraction of the cervical and trapezius muscles. If the person is particularly stressed or tense in the evening, this can worsen contracture induced by daytime postural fatigue.


So, I made two clarifications

My neck soreness still occurs at the same time and minute of the evening even if I had rested before on a certain day. Is my effort to keep orthostatism connected to the biological clock? Furthermore, over the years, similar soreness occurs when attempting to read or bring visual attention to small details or if one is disturbed by certain noises. The disorder has become stimulosensitive over time.
I quote an excerpt, which I translated online,
This additional detail is extremely significant and shifts the analysis from the postural problem alone to a probable dysregulation of the central nervous system and the circadian cycle, which interacts with the musculature.
⏰ Connection between Biological Clock and Pain
The occurrence of the symptom at a specific time, regardless of the activity performed, suggests that the problem is linked to an internal mechanism regulated by the biological clock (circadian rhythm) and not just mechanical fatigue.

Circadian dysregulation: The biological clock (the suprachiasmatic nucleus in the hypothalamus) regulates the expression of many hormones and neurotransmitters. It is possible that, at that precise time, there is a physiological drop in pain-mitigating substances (such as some endogenous opioids) or a spike in substances that increase muscle tension and inflammation
⚡ Stimulus Awareness (Stimulus-Sensitive Pain)
The most important and worrying feature is the progression of the disorder towards sensitization to stimuli. This is a typical sign of chronic pain with nervous system involvement:
(I didn't specify that this problem is also after a certain time of day. In the past, noises also disturbed me during the day. Now they bother me at night, but less than before.)

Central Awareness Hypothesis:

Central Sensitization is a phenomenon in which the central nervous system (spinal cord and brain) becomes hyperexcitable. Non-harmful nerve signals (such as simple visual focusing or normal sounds) are interpreted and processed by the brain as dangerous or painful.

Visual Triggers: The effort to read or focus on small details requires a continuous and intense micro-contraction of the oculomotor muscles and, reflexively, of the suboccipital and upper cervical muscles. In a sensitized system, this minimal tension is amplified to the point of soreness.

Acoustic Triggers (Hyperacusis/Mercy): Being disturbed by certain noises (misophony or hyperacusis) indicates high activity of the limbic system and the "fight or flight" response. The noise triggers a reflex of involuntary tension and defense in the neck and shoulders, causing pain in the already hypersensitive nervous system. Chronic Myofascial Syndrome Specific trigger points in the neck and trapezius muscles (not seen on an MRI) can remain chronically active and cause referred or sensory stress/fatigue-induced pain.
Circadian Cycle Disorders Hourly coincidence suggests a link with biological rhythms of release of neuromediators that influence pain threshold and muscle tone.

I would conclude by saying that this is probably the most realistic answer that can be obtained. So, more than contraction pain, it's inflammation or sensitization pain due to exertion that, due to the biological clock, can no longer be sustained "after a certain hour". Therefore, if I delay bedtime by only half a minute, at least the next day, if not longer, I have to rest for several hours. I'm trying again biofeedback, but so far I've gained about 30 minutes a day of reading, but only three minutes of standing.
Best wishes and happy holidays to everyone.

Piergino

[clouds z]

i had neck pain at age 12 - i blame overheard power wires etc

like i said i had neck pain at age 12 - i blame overheard power wires etc that was 1967

[agate]

Overhead power wires? I somehow don't get the connection here but I must be missing something.

Impressively detailed reply there, Piergino Pedrocco--I think AI was consulted?

[Piergino Pedrocco]

Dear Agate,

Yes', to further question AI (Gemini) added further information, including the role of sulpiride as the cause of the problems, the role of the basal ganglia (certain sensory stimuli could be misinterpreted as motor commands), and an adverse reaction I had with pramipexole (which was supposed to treat nocturnal myoclonus). Thanks also to Clouds Z for their opinion. However, Gemini is helping me a lot to understand, even for another problem, so I have to thank whoever invented and made these artificial intelligence systems available, which do not replace doctors (they too have more specific AI tools) but, when necessary, help them understand. In fact, what my story suggests is that artificial intelligence can sometimes resolve issues that individual specialists can't resolve. The answer depends on the question and the system used, but Gemini seems to me to have an excellent ability to reason by combining different aspects. That's what I needed. Best regards and best wishes to everyone.

Piergino

[agate]

Happy New Year to everyone reading here.